Furthermore, this hormone inhibits gastric emptying, gastrointestinal motility, and glucagon secretion [9,10,11]
Across pivotal trials, nausea occurred in 42% of participants on GLP-1 agonists, 45% on dual agonists, and 50% on triple agonists, with similar patterns for vomiting and diarrhea (Table 4 and Figure 2)
You should consider a form of backup contraception for a short time
Some patients may require an even higher dose of 2 mg weekly for optimal effect, particularly for weight management indications, though this should be approached cautiously with careful monitoring for adverse effects
Avoid straining during bowel movements: Straining during bowel movements can increase pressure in the gut and worsen diverticulitis symptoms